Videochat live sex webcast - Updating the icrp human respiratory tract model

Average and median estimates were calculated for f for each plutonium compound, that can be used as default values for specific chemical forms instead of the current reference types.Nevertheless, it was shown that the use of the current ICRP reference absorption types provides reasonable approximations.

updating the icrp human respiratory tract model-14

gta 4 final mod updating - Updating the icrp human respiratory tract model

In order to optimise the monitoring of potentially exposed workers, it is desirable to determine specific values of absorption for the compounds handled.

This study derives specific values of absorption rates for different chemical forms of plutonium from in vitro and animal (monkeys, dogs, mice, rats) experiments, and from human contamination cases.

The absorption of an actual compound is usually intermediate between the reference types.

Besides, the knowledge of a compound absorption influences the accuracy of the estimation of the dose from a given exposure as well as the definition of the monitoring programme.

As inhalation of an aerosol is the most likely route of intake for workers, a key parameter of the related dose assessment is the solubility of Pu deposited in the lungs.

Through the pulmonary absorption kinetics, it determines the fraction of the activity that is transferred from the lung to the blood and then to the systemic organs/tissues (primarily skeleton and liver) and, ultimately, to excretion.

The human respiratory tract model (HRTM) adopted by the ICRP (1994a) describes the deposition of an inhaled radionuclide in the respiratory tract, its clearance and the local dosimetry.

The clearance is due to the mucociliary transport of the deposited particles to the alimentary tract in competition with transport to the regional lymph nodes and with absorption into blood.

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