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Abstract: Leprosy or Hansen's disease is caused by an obligate intracellular pathogen i.e. Leprosy is a granulomatous disease of peripheral nerves and mucosa of the upper respiratory tract. Bowers KJ, Chow E, Xu H, Dror RO, Eastwood MP, Gregersen BA, Klepeis JL, Kolossvary I, Moraes MA, Sacerdoti FD, Salmon JK, Shan Y, Shaw DE (2006) Scalable Algorithms for Molecular Dynamics Simulations on Commodity Clusters. Abstract: For dynamic optimization problems, the aim of an effective optimization algorithm is both to find the optimal solutions and to track the optima over time.

Ki "Economic Load Dispatch: A New Hybrid Particle Swarm Optimization Approach"sept.11 2007.

Krus, "On Load Sensing Fluid Power Systems," Division of Fluid Power Control Department of Mechanical Engineering, Linkoping University, Sweden, 1988.

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The proposed four ports cylinder was simulated and parameters such as ports sizes, loads and pressures are varied during the simulation.

The hydraulic resisting forces, piston speed and mass flow rates are computed. Chenoweth, Aircraft flight control actuation system design vol.

Finite element analysis is a method to computationally model reality in a mathematical form to better understand a highly complex problem. it is a method of determine the most efficient, low cost & reliable operation of a power system by dispatching the available electricity generation resources to supply the load on the system.

Abstract: Analysis of the robot hand was analyzed using dedicated software for FEM analysis. in ANSYS, the geometry was updated and the structure meshed using 3D elements. Economic Load Dispatch(ELD) is one of important tasks which provide an economic condition for a power system.

Gao Yue-lin , Duan Yu-hong "A New Particle Swarm Optimization Algorithm with Random Inertia Weight and Evolution Strategy" International Conference on Computational Intelligence and Security Workshops 2007. Guimin Chen, Xinbo Huang, Jianyuan Jia and Zhengfeng Min " Natural Exponential Inertia Weight Strategy in Particle Swarm Optimization" 6th World Confress on Intelligent Control and Automation, June 21 - 23, 2006, Dalian, China. Jong-Bae Park, Yun-Won Jeong, Hyun Houng Kim and Joong-Rin Shin "An Improved Particle Swarm Optimization for Economic Dispatch with Valve-Point Effect" International Journal of Innovations in Energy Systems and Power, Vol. Therefore by emphasizing this protein as a drug target can help in the identification of novel drugs to cure leprosy. Black PN, Zhang Q, Weimar JD, Di Russo CC (1997): Mutational analysis of a fatty Acyl-coenzyme A Synthetase signature motif identifies seven amino acid residues that modulate fatty acid substrate specificity. Key words: cellular genetic algorithm, dynamic optimization, density dependence scheme Reference [1] R.

The activation of fatty acids by Acyl-Co A Synthetase is the need of de novo lipid biosynthesis, fatty acid catabolism and remodeling of biological membranes. The computation results indicate that new algorithms demonstrate their superiority respectively on both convergence and diversity.

Results show that the hydraulic resistance is significantly reduced in the proposed four ports actuators; and the proposed cylinders run faster than the conventional cylinders and a considerable amount of energyis saved as well.

Key words: Computational Hydraulic, Energy Efficient Actuators, Energy Saving in Hydraulic, Hydraulic Control Reference [1] P.

This causes a lot of heat generation and energy loss within the actuators.

The study investigates and analyzes the possibilities of reducing the hydraulic resistance and increasing efficiency of the hydraulic actuator.

Stukenbrock, "Toward maximum flexibility in working machinery, iht control in a mecalac excavator," 2004. Yao, "Energy-saving control of singlerod hydraulic cylinders with programmable valves and improved working mode selection," 2002. Eriksson, "Control Strategy for Energy Efficient Fluid Power Actuators: Utilizing Individual Metering," SE-581 83 Linköping, Sweden: Linköping University, 2007. There are various field of power system in which PSO is successfully applied.

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