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Audience Geography The audience geography data describes where visitors to this site over the past month are located, and how the site is ranked in popular countries. Engagement metrics help you understand how interested a site's visitors are with the site's content.
If a country is not listed, it is because Alexa does not have enough data for this site to rank/measure the site's popularity among that country's online population. The metrics are updated daily based on the trailing 3 months.
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The N terminus of arenavirus L protein contains an endonuclease presumably involved in “cap snatching.” Here, we employed the Lassa virus replicon system to map other L protein sites that might be involved in this mechanism.
Residues Phe-1979, Arg-2018, Phe-2071, Asp-2106, Trp-2173, Tyr-2179, Arg-2200, and Arg-2204 were important for viral m RNA synthesis but dispensable for genome replication.
L protein mediates the synthesis of two RNA species, m RNA terminating in the intergenic region and noncapped genomic or antigenomic RNA representing a full-length copy of the genome (8, 9).
The L RNA encodes the small matrix protein Z (2, 3) and the 200-k Da L protein (4).
NP and L protein are the minimal viral -acting factors required for replication and transcription of the genome (5–7).
The central domain of L protein harbors the RNA-dependent RNA polymerase (Rd Rp) (10–14), and the N terminus contains an endonuclease essential for transcription (15, 16).
The presence of the desired artificial mutation was ascertained by sequencing.
The more traffic a site gets, the more data we have to calculate estimated metrics.Tags: Adult Dating, affair dating, sex dating